{"id":445,"date":"2018-05-09T18:51:13","date_gmt":"2018-05-09T18:51:13","guid":{"rendered":"http:\/\/trejolab.ucsd.edu\/wordpress\/?page_id=445"},"modified":"2025-02-11T14:09:32","modified_gmt":"2025-02-11T22:09:32","slug":"publications-overlay-books","status":"publish","type":"page","link":"https:\/\/trejolab.ucsd.edu\/wordpress\/?page_id=445","title":{"rendered":"Publications"},"content":{"rendered":"

PUBLICATIONS<\/span><\/strong><\/h3>\n

\"\"<\/a><\/h3>\n

\u00a0<\/h3>\n

2025<\/h3>\n

________<\/p>\n

N. Cheng, M. Gonzalez Ramirez, C. Edwards and J. Trejo<\/strong> (2025). USP34 regulates endothelial PAR1 mRNA transcript expression and cellular signaling. Mol. Biol. Cell<\/strong>. Feb 1:36(2):ar12. Doi: 10.1091\/mbc.E24-07-0294<\/a><\/p>\n

O. Molinar-Inglis, K. Wiggins, A. Varma, Z. Del Mundo, J. M. Adame, A. Cozzo, O. Munoz, U-V Le, D. Trinh, A. C. Garcia, M. Cisneros-Aguirre, M.L.G Ramirez, J. Keyes, J. Zhang, M.A. Lawson, J. Trejo<\/strong> and D. A. Nicholas (2025). An optimized fractionation method reveals insulin-induced membrane surface localization of GLUT1 to increase glycolysis in LbT2 cells. Mol. Cell Endo.<\/strong>, Oct29:595:112405 Doi: 10.1016\/j.mce.2024.112405<\/a><\/p>\n

D. Fettes, V. Hazen, V. Reznik, D. Wingard, and J. Trejo. (2025). Thriving in Academia: A model of faculty development for successful, diverse, engaged faculty across career stages. J. Fac. Dev.<\/strong>, Vol. 39, No.1, Jan. pp.96-99 https:\/\/www.ingentaconnect.com\/contentone\/magna\/jfd\/2025\/00000039\/00000001\/art00014<\/a><\/p>\n

M. Corr, V. Reznik, D. Wingard, D. Fettes, V. Hazen, M. E. Martinez, and J. Trejo<\/strong>. (2025). Assessing Recruitment Strategies for Creating an Inclusive Tenure Track Faculty in Health Sciences: A Cohort Study. Health Sci. Rep<\/strong>. 8;e70363, https:\/\/doi.org\/10.1002\/hsr2.70363<\/a><\/p>\n

2024<\/h3>\n

________<\/p>\n

J. Trejo<\/strong> and G. Scita (2024) Scaling the Cellular Frontier: Mechanobiology, Tissue Dynamics and Function. Curr. Opin. Cell Biology<\/strong> Cell Signaling. Jan 11:86:102318. Doi: 10.1016\/j.ceb.2023.102318<\/a><\/p>\n

N. Cheng, J. M. Pimentel and J. Trejo<\/strong> (2024). Ubiquitin-driven G Protein-Coupled Receptor Inflammatory Signaling at the Endosome. Mini-review. Am J. Phys. Cell Phys<\/strong>, 326:C1605-1610, April 22, 2024, doi.org\/10.1152\/ajpcell.00161.2024<\/a><\/p>\n

L. M. Bohn, J. C. Garrison and J. Trejo.<\/strong> Chapter 2 \u201cCellular Receptors and Drug Concentration-Response Relationships\u201d (ed. S. Ingraham and L. Wecker) and Brody\u2019s Human Pharmacology, 7th edition. Elsevier.<\/strong> Copyright 2024.<\/p>\n

2023<\/h3>\n

________<\/p>\n

N. Cheng and J. Trejo<\/strong> (2023). An siRNA library screen identifies CYLD and USP34 as deubiquitinases that regulate GPCR-p38 MAPK signaling and distinct inflammatory responses. J. Biol. Chem<\/strong>, Oct 20, 299(12) 105370 doi: 10.1016\/j.jbc.2023.105370<\/a><\/p>\n

C. A. Birch, H. Wedegaertner, L. B. Ordu\u00f1a-Castillo, M. L. Gonzalez Ramirez, H. Qin and J. Trejo<\/strong> (2023). Endothelial APC\/PAR1 distinctly regulates cytokine-induced pro-inflammatory VCAM-1 expression. Front Mol. Biosci. Cell. Biochem.<\/strong> Aug 24;10:1211597. doi: 10.3389\/fmolb.2023.1211597<\/p>\n

H. Wedegaertner O. Bosompra, I. Kufareva and J. Trejo<\/strong> (2023). Divergent regulation of a-arrestin ARRDC3 function by ubiquitination. Mol. Biol. Cell.<\/strong>, May 24;mbcE23020055. doi:10.1091\/mbc.E23-02-0055<\/p>\n

J. A. Lawrence, P.A. Calvo, D. Ojeda-Juarez, H. Khuu, K. Soldau, D. Pizzo, J. Wang, A. Malik, T. Shay, E. Sullivan, B. Aulston. S. M. Song, J.A. Callendar, H. Sanchez, M. Geschwind, S. Roy, R. A. Rissman, J. Trejo<\/strong>, N.Tanaka, C. Wu, X. Chen, G. Patrick and C. Sigurdson (2023). Diminished neuronal ESCRT-0 function exacerbates AMPA receptor derangement and accelerates prion-induced neurodegeneration. J. Neurosci<\/strong>. May 24;43(21):3970-3984.<\/p>\n

M. Werner Washburne, J. Trejo<\/strong>, R. E. Zambrana, M. E. Zavala, A. Martinec, A. Riestra, T. Delgado, S. Edwards,T. Escobar, D. Jamison-McClung, M. Vasquez, I. Vera, M. Guerra, D. I. Marinez, E. Gonzalez, and R. L. Rodriguez (2023). Early Career Latinas in STEM: Challenges and Solutions. Cell<\/strong> 186, Nov 9, 2023 doi.org\/10.1016\/j.cell.2023.10.016<\/a><\/p>\n

A.G. Marshall, Z. Vue, H.K. Beasley, K. Neikirk, D. Stephens, C. N. Wanjalla, S.A.Damo, J. Trejo<\/strong>, P. Rodriguez- Aliaga, C. A. Headley, H. Shuler, K. Liu, N. Smith, E. Garza-Lopez, T. Barongan, E. Scudese, E. Spencer, J. Heemstra, A.D. Vazquez, S.A. Murray and A.J Hinton (2023). Diversity, Equity and Inclusion in the Laboratory: Strategies to Enhance Inclusive Laboratory Culture. Mol. Cell.<\/strong> 83, Nov 2, 2023 doi.org\/10.1016\/j.molcel.2023.09.011<\/a><\/p>\n

2022<\/h3>\n

________<\/p>\n

O. Molinar-Inglis, J. M. Wozniak, N.J. Grimsey, L. Ordu\u00f1a-Castillo, Y. Lin, N. Cheng, M. L. G. Ramirez, C. A. Birch, J. D. Lapek, D. J. Gonzalez and J. Trejo<\/strong> (2022). Phosphoproteomic analysis of thrombin- and p38 MAPK- regulated signaling networks in endothelial cells. J. Biol. Chem<\/em><\/strong>. <\/em>Apr;298(4)101801, 1-17.<\/p>\n

H. Wedegaertner, W.-A. Pan, C. Gonzalez, D. J. Gonzalez and J. Trejo <\/strong>(2022). The a-arrestin ARRDC3 is an emerging multifunctional adaptor protein in cancer. Antioxid. Redox Signal<\/em><\/strong>. May;36(13-15):1066-1079.<\/p>\n

B. Andrade, H. C. Medina-Munoz, E.T. Monta\u00f1o, J. N. Roa, R. G. S\u00e1nchez, J. Tat, S. Hurst, M. E. Mouchka, J. Trejo<\/strong> and M. L. G. Ramirez (2022). COVID-19 threatens faculty diversity: postdoctoral scholars call for action. Mol. Biol. Cell<\/em><\/strong>, Voices<\/em>. Mar 1;33(3).<\/p>\n

D. A. Nicholas, J. Trejo<\/strong> and C. M. Termini (2022). Building a laboratory and networks during the COVID-19 pandemic. Trends in Biochem. Sciences<\/em><\/strong> Sept;47(9):725-727.<\/p>\n

2021<\/h3>\n

________<\/p>\n

O. Molinar-Inglis, C. A. Birch, D. A. Nicholas, L. Ordu<\/span>\u00f1<\/span>a-Castillo<\/span> M. Cisneros-Aguire, A. Patwardhan, B. Chen, N.J. Grimsey, L. J. Coronel, H. Lin, P.K.G. Menzies, M. A. Lawson, H. H. Patel and J. Trejo <\/b>(2021)\u00a0 aPC\/PAR1 confers endothelial anti-apoptotic activity via a discrete \u03b2-arrestin-2-mediated Sphk1-S1PR1-Akt signaling axis.<\/span> <\/i><\/b>Proc. Natl. Acad. Sci. USA<\/span><\/i><\/b>. <\/i><\/b>Vol. 118 No. 29 e2106623118.<\/span><\/p>\n

Rada CC, Mejia-Pena H, Grimsey NJ, Cordova IC, Olson J, Wozniak JM, Gonzalez DJ, Nizet V, and J. Trejo<\/strong> (2021) Heat shock protein 27 activity is linked to endothelial barrier recovery after pro inflammatory GPCR-induced disruption. Sci. Signal.<\/strong> <\/em>14, eabc1044, 31 Aug.\u00a0<\/p>\n

Arakaki AKS, Pan WA, Wedegaertner H, Roca-Mercado I, Chinn L, Gujral TS and J. Trejo<\/strong> (2021) \u03b1-arrestin ARRDC3 tumor suppressor function is linked to GPCR-induced TAZ activation and breast cancer metastasis.\u00a0 J. Cell Sci.<\/strong><\/em> 134 (8):jcs254888.<\/p>\n

Patwardhan A, N Cheng and J. Trejo<\/strong> (2021) Post-Translational Modifications of G Protein-Coupled Receptors Control Cellular Signaling Dynamics in Space and Time.\u00a0 Pharm. Rev. <\/em><\/strong>Jan, 73:120-151<\/p>\n

Birch CA, O Molinar-Inglis, and J. Trejo<\/strong> (2021). Subcellular hot spots of GPCR signaling promote vascular\u00a0 inflammation.\u00a0 Curr. Opin. in Endo. Metabo. Research.<\/em> <\/strong>Feb;16:37-42.<\/p>\n

Trejo<\/strong>, D. Wingard, V. Hazen, A. Bortnick, K. Van Hoesen, A. Byars-Winston, C. Pfund and V. Reznik. (2021). A System-wide Health Sciences Faculty Mentor Training Program Is Associated with Improved Mentoring Effectiveness and Institutional Climate. J. Clin. Trans. Sci.<\/em><\/strong> Dec 23;6(1);e18. doi.org\/10.1017\/cts.2021.883<\/a><\/p>\n

2020<\/h3>\n

________<\/p>\n

Zhou X, Z Yanghao, O Molinar-Inglis, MR Kunkel, M Chen, T Sun, J Ziang, JYJ Shyy, J. Trejo<\/strong>, AC Newton, and J Zhang (2020) Location-specific inhibition of Akt reveals regulation of mTORC1 activity in the nucleus. Nat. Communications <\/em><\/strong>Nov 30: 11(1): 6088<\/p>\n

Nicholas DA, VS Knight, KJ Tonsfeldt, T Terasaka, O Molinar-Inglis, SBZ Stephens, J. Trejo, <\/strong>AS Kauffman, PL Mellon, and MA Lawson (2020) GLUT1-mediated glycolysis supports GnRH-induced secretion of luteinizing hormone from female gonadotropes. Sci. Reports <\/em><\/strong>Aug 3;10(1):13063.<\/p>\n

Keyes, A.\u00a0Ganesan, O. Molinar-Inglis, A.\u00a0Hamidzadeh, J. Zhang, M. Ling, J.<\/strong>Trejo,\u00a0<\/strong>A.\u00a0Levchenko, and J.\u00a0Zhang.\u00a0Signaling Diversity Enabled by\u00a0Rap-1-Regulated Plasma Membrane ERK\u00a0with Distinct Temporal\u00a0Dynamics.\u00a0eLife <\/em><\/strong>2020 May 26;9:e57410.\u00a0doi: 10.7554\/eLife.57410<\/p>\n

Lin Y, Wozniak JM, Grimsey NJ, Girada S, Patwardhan A, Molinar-Inglis O, Smith TH, Lapek JD, Gonzalez DJ, Trejo J<\/strong>. (2020) Phosphoproteomic analysis of protease-activated receptor-1 biased signaling reveals unique modulators of endothelial barrier function. Proc Natl Acad Sci U S A<\/span><\/strong><\/em>. 2020 Mar 3;117(9):5039-5048. doi: 10.1073\/pnas.1917295117<\/p>\n

J. Trejo<\/strong> (2020) The burden of service for faculty of color to achieve diversity and inclusion: the minority tax. Mol. Biol. Cell,<\/em> <\/strong>31: 2752-2754.<\/p>\n

2019<\/h3>\n

________<\/p>\n

Grimsey NJ, Lin Y, Narala R, Rada CC, Mejia-Pena H, Trejo J.<\/strong> (2019) G protein-coupled receptors activate p38 MAPK via a non-canonical TAB1-TAB2- and TAB1-TAB3-dependent pathway in endothelial cells. J Biol Chem.<\/strong><\/em> 294 (15) : 5867-5878. doi: 10.1074\/jbc.RA119.007495.<\/p>\n

Dores MR, Trejo J.<\/strong> (2019) Endo-lysosomal sorting of G-protein-coupled receptors by ubiquitin: Diverse pathways for G-protein-coupled receptor destruction and beyond. Traffic<\/strong><\/em> 20 (2) : 101-109 doi:10.1111\/tra.12619. Review<\/p>\n

Wingard D, Trejo J<\/strong>, Gudea M, Goodman S and Reznik V (2019) Faculty Equity, Diversity, Culture and Climate Change in Academic Medicine: \u00a0A Longitudinal Study. \u00a0J. Nat. Med. Assoc.,<\/em><\/strong> 11:(1): 46-53.<\/p>\n

Ochoa SD, Dores MR, Allen JM, Tran T, Osman M, Vazquez-Castellanos NP, Trejo J<\/strong> and Zayas R (2019) A modular laboratory course using planarians to study genes involved in tissue regeneration. \u00a0Biochem. and Mol. Biol. Education<\/strong>. <\/em>Sep;47(5):547-559.<\/p>\n

2018<\/h3>\n

________<\/p>\n

J. Grimsey, R. Narala, C. C. Rada, S. Mehta, B.S. Stephens, I. Kufareva, J. Lapek, D. J. Gonzalez, T.M. Handel, J. Zhang and J. Trejo<\/strong> (2018). A tyrosine switch on NEDD4-2 E3 ligase transmits GPCR inflammatory signaling. Cell Reports<\/strong><\/em>, 18:24(12):3312-3323<\/p>\n

M.R. Dores and J. Trejo<\/strong> (2018). Endo-lysosomal sorting of G protein-coupled receptors by ubiquitin: Diverse pathways for GPCR destruction and beyond. Traffic<\/strong><\/em>, Oct 23. doi: 10.1111\/tra.12619.<\/p>\n

Arakaki AKS, Pan WA, Trejo J<\/strong>. GPCRs in Cancer: Protease-activated Receptors, Endocytic Adaptors and Signaling. Int J Mol Sci<\/strong> <\/em>2018, 19(7) 1886, 1-24<\/p>\n

Kroeger H, Grimsey N, Paxman R, Chiang WC, Plate L, Jones Y, Shaw PX,\u00a0Trejo J<\/strong>, Tsang SH, Powers E, Kelly JW, Wiseman RL, Lin JH. The Unfolded Protein Response Regulator ATF6 Promotes Mesodermal Differentiation.\u00a0Sci Signal<\/strong><\/em>\u00a02018 Feb 13; 11(517)<\/p>\n

Arakaki AKS, Pan WA, Lin H,\u00a0Trejo J<\/strong>. The\u00a0\u03b1-arrestin ARRDC3 suppresses breast carcinoma invasion by regulating G-protein coupled receptor lysosomal sorting and signaling.\u00a0J Biol Chem\u00a0<\/em><\/strong>2018 Mar 2;293(9):3350-3362
<\/span><\/p>\n

2017<\/h3>\n

________<\/p>\n

Smith TH, Li JG, Dores MR,\u00a0<\/span>Trejo J<\/b>. Protease-activated Receptor-4 and Purinergic receptor P2Y12 dimerize, co-internalize, and activate Akt Signaling via Endosomal Recruitment of\u00a0\u03b2-arrestin.\u00a0<\/span>J Biol Chem.\u00a0<\/i><\/b>2017 Aug 18;292(33):13867-13878<\/span><\/p>\n

Hamilton JR,\u00a0<\/span>Trejo J<\/b>. Challenges and Opportunities in Protease-Activated Receptor Drug Development.\u00a0<\/span>Annu Rev Pharmacol Toxicol<\/i><\/b>\u00a02017Jan 6l57:349-373<\/span><\/i><\/p>\n

Trejo J<\/b>. A Reflection on Faculty Diversity in the 21st Century.\u00a0<\/span>Mol Biol Cell\u00a0<\/i><\/b>2017 Nov 1:28(22):2911-2914<\/span><\/p>\n

2016<\/h3>\n

________<\/p>\n

Smith TH, Coronel LJ, Li JG, Dores MR, Nieman MT,\u00a0<\/span>Trejo J<\/b>. Protease-activated Receptor-4 Signaling and Trafficking Is Regulated by the Clathrin Adaptor Protein Complex-2 Independent of\u00a0\u03b2-arrestins.\u00a0<\/span>J Biol Chem<\/i><\/b>\u00a02016 Aug 26;291(35):18453-64<\/span><\/p>\n

Dores MR, Grimsey NJ, Mendez F, <\/span>Trejo\u00a0J.<\/b> ALIX regulates the ubiquitin-independent lysosomal sorting of the purinergic P2Y1 receptor via a YPX3L motif.\u00a0<\/span>PLoS One<\/i><\/b>\u00a02016, 11(6):e0157587.<\/span><\/p>\n

Grimsey NJ and\u00a0<\/span>Trejo J<\/b>. Integration of endothelial protease-activated receptor-1 inflammatory signaling by ubiquitin.\u00a0<\/span>Curr Opin Hematol<\/i><\/b>\u00a02016, 23(3):274-279.<\/span><\/p>\n

Grimsey NJ, Coronel LJ, Cordova IC, and\u00a0<\/span>Trejo\u00a0J<\/b>. Recycling and endosomal sorting of protease-activated receptor-1 is distinctly regulated by Rab11A and Rab11B Proteins.\u00a0<\/span>J Biol Chem <\/i><\/b>2016, 291:2223-2236.<\/span><\/p>\n

\n

A complete list of works by JoAnn Trejo<\/em><\/a><\/p>\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

PUBLICATIONS \u00a0 2025 ________ N. Cheng, M. Gonzalez Ramirez, C. Edwards and J. Trejo (2025). USP34 regulates endothelial PAR1 mRNA transcript expression and cellular signaling. Mol. Biol. Cell. Feb 1:36(2):ar12. …<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-445","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/trejolab.ucsd.edu\/wordpress\/index.php?rest_route=\/wp\/v2\/pages\/445"}],"collection":[{"href":"https:\/\/trejolab.ucsd.edu\/wordpress\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/trejolab.ucsd.edu\/wordpress\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/trejolab.ucsd.edu\/wordpress\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/trejolab.ucsd.edu\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=445"}],"version-history":[{"count":46,"href":"https:\/\/trejolab.ucsd.edu\/wordpress\/index.php?rest_route=\/wp\/v2\/pages\/445\/revisions"}],"predecessor-version":[{"id":986,"href":"https:\/\/trejolab.ucsd.edu\/wordpress\/index.php?rest_route=\/wp\/v2\/pages\/445\/revisions\/986"}],"wp:attachment":[{"href":"https:\/\/trejolab.ucsd.edu\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=445"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}